抄録
Biogenic high-basic polyamines ionically bind to acidic molecules such as ATP, Acetyl-CoA, fatty acids, acid polysaccharides, polyphosphoric acids, and nucleic acids (RNA and DNA) to express its various biological functions in bacterial cells. Following the taxonomy of Bacteria (Eubacteria) and Archaea (Archaebacteria), we have analyzed polyamines comprehensively in the acid extracts from bacterial cells of approximately 7,000 strains (5,000 species) from 1983 to 2023. In Maebashi Institute of Technology, Maebashi, Gunma, Japan, we analyzed 1,191 bacterial strains supplied from microbial culture collections and published their cellular polyamines on 13 original papers in J. Jpn. Soc. Extremophiles, 2007-2023. Thirty-five kinds of linear, branched and acetylated polyamines were quantitatively analyzed using high-performance liquid chromatography (HPLC) and high-performance gas chromatography-mass spectrometry (HPGC-MS) and were calculated as μmol/g wet weight of cells. Two to ten polyamine components were detected in an archaeon as well as a bacterium. Distributions of the diamines, diaminopropane, putrescine and cadaverine, the triamines, spermidine, norspermidine and homospermidine and the tetra-amines, spermine, norspermine and thermospermine were varied chemotaxonomically within bacteria and archaea. Their polyamine distribution patterns were not corelated to their chemolithoautotrophic, photosynthetic and diazotrophic activities, and were dependent on their optimum growth temperature in addition to their evolutionary phylogenetic positions. Extremely/hyper thermophilic bacteria and archaea contained long polyamines such as linear penta-amines, linear hexa-amines, tertiary-branched tetra-amines and quaternary-branched penta-amines. Acidic, alkaliphilic and halophilic growth conditions were insignificant to change of polyamine distribution profiles. Agmatine, putrescine and spermidine levels in fatty acid-producing human intestinal bacteria are discussed.
https://ror.org/01x05rm94 
