Japanese Journal of Microbiology
Print ISSN : 0021-5139
Enhancement of 32P Incorporation into Phospholipids in Cultured Cells by Sendai Virus of Parainfluenza Type 1
Hiroshi SHIBUTAKoichi YAMAURAKoichi HIRANOMinoru MATUMOTO
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1971 年 15 巻 2 号 p. 185-191

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Sendai virus infection induced enhancement of 32P incorporation into phospholipids in chick embryo, monkey kidney and bovine kidney cells, as previously observed in chorioallantoic membranes of chick embryos. These findings indicate that phospholipid synthesis is enhanced upon Sendai virus infection. Ultraviolet irradiation abolished the ability of the virus to induce the enhanced synthesis of phospholipids, a fact suggesting that the phenomenon depends upon infectivity of the virus. Gamma irradiation of host cells little affected the enhanced 32P labeling of cellular phospholipids, suggesting that the function of host cell DNA may not be directly involved in the phenomenon.
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