抄録
Currently, it is widely recognized that drug transporters play important roles as major determinants for pharmaco-kinetic properties of drugs. During about 30 years, we have investigated membrane transport of drugs via carriers,with taking various novel techniques such as membrane vesicles and molecular biology into this research field, andreported some important novel findings on the intestinal absorption and renal excretion of drugs. Furthermore, wehave developed clinical research of drug transporters to accomplish our motto “From Bench to Bedside”. In thisreview, we would like to look back on the history of drug transporter research, mainly focusing on our studies, anddescribe the future perspectives.
