Cell Surface Modification with Polymers for Biomedical Studies

Abstract

Surface modification of living cells with natural or synthetic polymers is a useful tool in biomedical engineering. Various functional groups and bioactive substances can be introduced to the cell surface through covalent conjugation, hydrophobic interaction, or electrostatic interaction. In this review, we provide an overview of methods and polymers employed in cell surface modification, and also discuss their applications to transplantation of islets of Langerhans for treatment of type 1 diabetes.