Syntheses of Phospholipid Hybrid-Membrane and Realization of High Performance by the Incorporation of Metal Complexes

Abstract

Discussions are focused on the characteristics of some liposomes formed by the assembled lipid molecules. Especially, phase transition temperature, mechanical strength and morphology of lipid assemblies. (micro phase separation) are affected by the species and ratio of mixed lipids in hybrid liposomes. Physico-chemical characteristics of hybrid liposomes, in which macromolecules are introduced as one component or polymerizable lipids are post-polymerized in situ, are discussed and compared with human erythrocytes membrane. The hybrid liposomes, in which heme derivatives are embedded in between layers of membrane structure, are introduced as artificial oxygen carrier comparable to human erythrocyte.