2015 Volume 58 Pages 28-36
It is well known that micronized or especially nano-sized active pharmaceutical ingredients or drug carriers will show quite different performances in a human body from normal-sized drugs. Nowadays these facts are widely reported. This is considered based on the characteristics that nano-sized particles have special affinity to tissues of human body and can be delivered to a specific diseased area in the body. Nano technologies are applied to the development of more effective or useful drug products. The author would like to explain some examples of nano-sized drug technologies, and also many problems in the powder unit operations in manufacturing drug products which should be dissolved under regulatory requirements.
