トリコテセン系毒素産生制御機構の解明と汚染低減化に向けた基盤研究

前田 一行; 中嶋 佑一; 市川 雛代; 鬼頭 良幸; 古﨑 貴大; 斎藤 臣雄; 本山 高幸; 長田 裕之; 小林 哲夫; 木村 真

doi:10.2520/myco.64.69

“Fusarium toxin today”

Basic research of the regulation mechanisms of trichothecene production for reduction of the mycotoxin contamination

Kazuyuki MAEDA, Yuichi NAKAJIMA, Hinayo ICHIKAWA, Yoshiyuki KITOU, Takahiro KOSAKI, Tamio SAITO, Takayuki MOTOYAMA, Hiroyuki OSADA, Tetsuo KOBAYASHI, Makoto KIMURA

Author information

Kazuyuki MAEDA
Department of Biological Mechanisms and Functions, Graduate School of Bioagricultural Sciences, Nagoya University
Yuichi NAKAJIMA
Department of Biological Mechanisms and Functions, Graduate School of Bioagricultural Sciences, Nagoya University
Hinayo ICHIKAWA
Department of Biological Mechanisms and Functions, Graduate School of Bioagricultural Sciences, Nagoya University
Yoshiyuki KITOU
Department of Biological Mechanisms and Functions, Graduate School of Bioagricultural Sciences, Nagoya University
Takahiro KOSAKI
Department of Biological Mechanisms and Functions, Graduate School of Bioagricultural Sciences, Nagoya University
Tamio SAITO
RIKEN Center for Sustainable Resource Science
Takayuki MOTOYAMA
RIKEN Center for Sustainable Resource Science
Hiroyuki OSADA
RIKEN Center for Sustainable Resource Science
Tetsuo KOBAYASHI
Department of Biological Mechanisms and Functions, Graduate School of Bioagricultural Sciences, Nagoya University
Makoto KIMURA
Department of Biological Mechanisms and Functions, Graduate School of Bioagricultural Sciences, Nagoya University

Keywords: chemical array, chemical library, mycotoxin inhibitor, trichothecene mycotoxin

JOURNAL FREE ACCESS

2014 Volume 64 Issue 1 Pages 69-74

DOI https://doi.org/10.2520/myco.64.69

Details

Abstract

Novel bioactive substances that regulate trichothecene production are in great demand both as tools for basic research and as control agents for reduction of mycotoxin contamination. Using compounds from the RIKEN Natural Product Depository (NPDepo) library, we are now screening for activators and inhibitors of trichothecene production. In this symposium, we describe the outlines of our recent progress on the regulation mechanisms of trichothecene production.

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