数種Penicillium属菌によるアルカロイドの産生

抄録

Some species of the genus Penicillium (P. palitans, P. expansum and P. farinosum) were examined for the ability to produce nitrogen-containing mycotoxins (alkaloids) on synthetic, complex media, summer wheat and apple juice in the submerged and surface culture. Bioproduction of clavine and benzodiazepine alkaloids was observed in all media tested in surface conditions. However, the essential differences were found in the total amounts of alkaloids as well as in the ratio of separate components and their distribution between the mycelium and culture broth. It was suggested that a correlation exists between the ability of fungi to produce N-containing mycotoxins (alkaloids) on artificial media and that on natural substrates.