實驗的膵障害犬における脂肪の消化吸收

抄録

We studied on digestion and absorption of fat in the pancreas impaired dog with respect to the following points:
(a) Determination of fat in feces.
(b) Determination of fat in the lymphliquid by means of experimental fistula of thoracic duct.
(c) Determination of vitamine A, administered per os, in blood and lymphliquid.
Van de Kammer's method B was adapted for the sake of (a) and (b). Spectrophotometer was used for the determination of (c) as indicated in Fujita-Aoyama G. D. H. method.
In the consequence of the study of fat in feces, it was elucidated that both digestion and absorption of fat were disturbed and a sign of recovery was not shown in the dog which pancreas was totally resected.
When the pancreatic duct was ligated, the absorption of fat was at first impeded gravely, one week thereafter the tendency to the recovery was observed.
Remarkable change was not recognized in the dog which two-thrid and eight-tenth of pancreas was respectively resected, as well as in the dog suffered from experimentally induced allergic pancreatitis.
As the results of the determination of fat in the lymphliquid, it was ascertained that the absorption of totally pancreatomized dog was quite out of order.
When the pancreatic duct was ligated, the absorption of fat was disturbed for the first one week, and thereafter resumed better.
By means of the determination of absorbed vitamine A in the lymphliquid and in blood simultaneously, it was observed that most vitamine A was absorbed in the lymphliquid for the normal dog, and its absorption was impeded in the totally pancreatomised dog.
Further, in dog with ligated pancreatic duct, the quantity of vitamine A in blood was counted nearly as much as in normal one while in the former the amount of vitamine A in lymphliquid far less than that in the latter.