抄録
Objective: We previously investigated central obesity, metabolic syndrome, smoking, and reflux symptoms as risk factors for reflux esophagitis (RE) in healthy individuals. The aim of this study was to determine if dietary habits and upper gastrointestinal diseases are risk factors for RE.
Methods: A total of 1,531 subjects who visited the Department of General Medicine, National Center for Global Health and Medicine from January 2003 through November 2008 for annual Ningen Dock health check-up were surveyed. We used multivariate logistic regression analysis to evaluate selected risk factors for RE.
Results: RE was identified in many of the male subjects and was increased by fatty foods in the female subjects. Increased prevalence of RE was associated with presence of hiatus hernia. The presence of atrophic gastritis was associated with decreased prevalence of RE.
Conclusion: Guidance on reducing fat intake in patients with RE would be especially effective in women. The prevalence of RE was related to presence of hiatus hernia and atrophic gastritis.
