整形外科と災害外科
Online ISSN : 1349-4333
Print ISSN : 0037-1033
ISSN-L : 0037-1033
EOG 滅菌された凍結乾燥骨の臨床使用上の問題点
吉岩 豊三加来 信広平 博文津村 弘
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2004 年 53 巻 2 号 p. 436-440

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We observed four patients on whom bone allograft sterilized with ethylene oxide gas was used intraoperatively to fill bone defects after curettage. Average age was 16.7 years. They consisted of two males and two females. Two had single bone cyst, one giant cell tumor, and one chondroblastoma. All cases showed swelling and redness around their wound, and discharge from an early period after surgery. Although postoperative infection was suspected, all cultivation was found to be bacteria free. There was no elevation in C-reactive protein from the second week after surgery. Three cases underwent surgical treatment. A case receiving conservative treatment with immunosuppressant agent showed good results of gradual wound healing. We suggest inflammation was induced by residual ethylene oxide of the freeze-dried bone.

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© 2004 西日本整形・災害外科学会
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