骨肉腫の治療

抄録

Forty-seven patients with osteosarcoma were classified into five groups by chemotherapeutic regimen. The first group (included ten patients) was treated with nitromin, azan and sarkomycin before 1960, the second group (twelve patients) with mitomycin C from 1961 to 1970, the third group (eight patients) with VAMT from 1971 to 1974, the fourth group (eight patients) with adriamycin from 1975 to 1977, and finally the fifth group (four patients) with adriamycin and methotrexate since 1978.
The first showed 0% of five-year cumulative survival rate, the second 24.9%, the third 12.5%, and the fourth 37.5%.
Twelve patients with systemic chemotherapy since 1975 had 49.6% of five-year cumulative survival rate, and the other thirty-five patients before 1974 with non-systemic chemotherapy had 11.4%.