Wells et al. (1968) reported that the hypocalcemic action of imidazole was partially prevented by prior administration of isoproterenol and theophylline.
And we have reported that imidazole promotes calcification in the widened growth plate of HEBP induced rachitic rats.
So, in this time, we report the effect of imidazole on fracture healing in two cases, normal rats and HEBP induced rachitic rats. Rats were female Fisher 344.
We examined calcification in early fracture callus.
The results suggested that Imidazole promoted calcification in fracture callus of HEBP induced rachitic rats.
But we considered that imidazole did not clearly promote calcification in fracture callus of normal rats.
