関節周囲の石灰沈着症に対するHEBP (EHDP) の投与経験

抄録

We investigated the administration of etidronic acid to patients with painful calcification around the joint. There were six patients, who were all women aged 35-55. Five were around the shoulder and one was around the knee. Their primary subjective complaint was severe pain and primary objective finding was limitation of range of motion. All patients had calcifications found on plain radiographs. We administered etidronic acid, at a dosage of 400mg per day. The period of administration was from 10 days to 12 weeks and the period of follow up was from 2 months to 2 years. As their symptoms improved, the calcifications reduced in size or disappeared on plain radiographs. In the future, we will consider etidronic acid useful in the treatment of the calcification around the joint.