In the previous study we reported the calcification-promoting effect of triiodothyronine (T3) in the growth plate of HEBP-induced-rickets rats in soft tissue radiographs.
The present study corroborates the same effect histologically. T3 treated rats showed increased thickness and cell number of the hypertrophic cell zone when compared to the control group. It is suggested that T3 can stimulate maturation and growth of the hypertrophic cells, and subsequently enhanced calcification, i. e. calcification-promoting effect.
