Newquinolone is among the most frequentory used drugs in antibacterial medicines. However, this drug has been reported to cause episodes of convulsive seizures. In one particular case, it was reported that the patient treated with the combination of antibacterial drug enoxacin and the nonsteroid anti-inflammatory drug fenbufen had convulsive seizures. The convulsion caused fracture dislocation of the shoulder joint. The patient was a 33-year-old male who was diagnosed with inflammation of upper respiratory tract. He was given orally a daily dose of 600mg of fenbufen and a daily dose of 600mg of enoxasin. Convulsive seizure occured in the second day of this combination therapy and caused him to collapse at work. He was taken by ambulance to the hospital where he displayed signs of acute renalfailure. His general condition improved after 4 weeks, 8 sessions, of hemodialysis therapy, after which he was surgically treated for osteosynthesis of fracture dislocation of the shoulder. In this paper, we reported precautions for this combination therapy.
