上腹部外科的疾患開腹時の消化管内大腸菌の研究

主として血清学的同定について

抄録

At laparatomy of surgical disease in the upper abdomen, the specimens were collected from the gall bladder, common bile duct, duodenum, jejunum, ileum and trnsverse colon. From each of specimens, E. coli was isolated and O-serotypes were identified, and thus the ecology and physiopathology of E. cole in human intestine were examined.
1) The examination of the biliary system, E. coli was detected in choledocholithiasis with the highest percentage (50%) and cholecystolithiasis (15%), and stomach cancer (9%) were followed. No E. coli was found in ulcer froup.
2) In the duodenum and jejunum, the incidence of E. coli was the highest in the froup of choledocholithiasis (50%, 50%), followed by stomach cancer (29%, 32%), cholecystolithiasis (15%, 18%) and ulcer (5%, 4%).
3) In the terminal ileum, the detection rate was conciderably high in the following three groups: stomach cancer (72%), cholecystolithiasis (64%), choledocholithiasis (63%). On the contrary, ulcer group showed the lowest rate of 30%.
4) The group E. coli was found in the terminal ileum was associated with some other pathologic conditions than the group E. coli was found in the transverse colon only.
5) In the case E. coli was found in the upper digestive tracts above jejunum including the biliary system, this organism was found in the whole intestinal tracts as predominant resident, and only one species was found as a rule. In the group E.coli was detected only in the transverse colon, three serothpes were identified.
6) The serothpes from 0-1 to 0-25 and so called toxic E. coli were mostly detected in the upper digestive tracts. However, no this type of phenomomen was observed in the enteropathogenic E. coli.