抄録
As models of clinical hypertensive intracerebral hematomas, intracerebral hematomas were induced experimentally in 26 mongrel dogs. The CT images of the hematomas during healing were compared with histological findings to determine the cause of ring enhancement in contrast enhanced CT.
The ring enhancement appeared at almost the same time in all dogs, 9 days after formation of the hematomas. Formation of many new capillaries in the peripheral region of the hematomas was seen from day 9 and the ring enhancement was found to be closely associated with these new capillaries. Electron microscopy showed that these newly formed capillary vessels had a similar ultrastructure to those of the muscle. These vessels seemed to have no blood brain barrier. Thus the ring enhancement was attributed to the accumulation of contrast medium in these newly formed vessels and its leakage from the vessels owing to their increased permeability.
