Abstract
Xenon-enhanced computed tomography (CT) was done in monkeys to study the enhancement effect and clearance rate of xenon in the normal and the embolized brain. The embolization was performed by using barium-impregnated silicone spheres blown through the internal carotid artery which were detectable by CT. The normal brain was enhanced symmetrically, first in the gray matter, then in the white matter, while the infarcted brain showed significantly diminished enhancement. By obtaining serial CT scans for 10 minutes, the clearance rate of xenon and the cerebral blood flow were calcurated. Xenon-enhanced CT may be used for clinical study of regional cerebral blood flow.
