Post-irradiation Brain Tumors

Shinichiro OKAMOTO; Hajime HANDA; Junkoh YAMASHITA; Yasuhiko TOKURIKI; Mitsuyuki ABE

doi:10.2176/nmc.25.528

Shinichiro OKAMOTO, Hajime HANDA, Junkoh YAMASHITA, Yasuhiko TOKURIKI, Mitsuyuki ABE

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Keywords: brain neoplasms, post-irradiation neoplasms, meningioma, glioblastoma, radiation therapy

JOURNAL FREE ACCESS

1985 Volume 25 Issue 7 Pages 528-533

DOI https://doi.org/10.2176/nmc.25.528

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Abstract

Four cases of brain tumor—three meningiomas and one glioblastoma—that developed after radiation therapy are reported. The location and course of each tumor were highly suggestive of a pathogenetic role of the preceding irradiation in the development of the tumor. A review of the literature revealed that there is evidence for a causative role of irradiation in the development of brain tumors, although there has been no definitive epidemiological study.

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