Abstract
Diffuse lymphocytic infiltration of the pituitary gland occurring in temporal relation to gestation was found in a 30-year-old female who had a suprasellar mass that caused bitemporal hemianopsia. The histology and pathogenesis of this lesion is discussed. Endocrinological examination showed a lower value of prolactin and growth hormone in her serum, but the other pituitary hormones were normal. From the results of these clinicopathological examinations it is unable to propose any opinion as to whether this is an autoimmune disease or not at the present time. However, it seemed that the hypopituitarism was present following destruction of the hormone secreting cells by lymphocytic infiltration. This observation suggests that hormone replacement therapy is required at an early stage.
