Immunohistochemical Analysis of Tumor-infiltrating Lymphocytes and Adhesion Molecules (ICAM-1, NCAM) in Human Gliomas

Ryuya YAMANAKA; Ryuichi TANAKA; Takafumi SAITO

doi:10.2176/nmc.34.583

Ryuya YAMANAKA, Ryuichi TANAKA, Takafumi SAITO

著者情報

キーワード: immunohistochemistry, intercellular adhesion molecule-1, neural cell adhesion molecule, T lymphocyte subset, tumor-infiltrating lymphocyte

ジャーナルフリー

1994 年 34 巻 9 号 p. 583-587

DOI https://doi.org/10.2176/nmc.34.583

詳細

抄録

The presence of tumor-infiltrating lymphocytes (TILs) and the expression of adhesion molecules were examined in 12 glioma tissues. Most TILs were T lymphocytes, and both cytotoxic/suppressor and helper/inducer T lymphocyte phenotypes were found. Neural cell adhesion molecule was intensely expressed in 11 gliomas, and intercellular adhesion molecule-1 (ICAM-1) in seven. Many TILs were found only in gliomas expressing ICAM-1, but there was no relationship with clinical course in the patients.

責任著者(Corresponding author)

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