Human Interferon—β Therapy for Cerebral Primitive Neuroectodermal Tumors —Two Case Reports—

Satoshi TANAKA; Masaaki OKADA; Mineko MURAKAMI; Makoto HIRAKAWA; Shinya MANAKA; Tadashi NAGASHIMA

doi:10.2176/nmc.35.82

Human Interferon—β Therapy for Cerebral Primitive Neuroectodermal Tumors

—Two Case Reports—

Satoshi TANAKA, Masaaki OKADA, Mineko MURAKAMI, Makoto HIRAKAWA, Shinya MANAKA, Tadashi NAGASHIMA

著者情報

Satoshi TANAKA
Department of Neurosurgery, Ichihara Hospital, Teikyo University School of Medicine

Masaaki OKADA
Department of Neurosurgery, Ichihara Hospital, Teikyo University School of Medicine

Mineko MURAKAMI
Department of Neurosurgery, Ichihara Hospital, Teikyo University School of Medicine

Makoto HIRAKAWA
Department of Neurosurgery, Ichihara Hospital, Teikyo University School of Medicine

Shinya MANAKA
Department of Neurosurgery, Ichihara Hospital, Teikyo University School of Medicine

Tadashi NAGASHIMA
Department of Neurosurgery, Ichihara Hospital, Teikyo University School of Medicine

責任著者(Corresponding author)

キーワード: brain tumor, children, human interferon-β, primitive neuroectodermal tumor

ジャーナルフリー

1995 年 35 巻 2 号 p. 82-86

DOI https://doi.org/10.2176/nmc.35.82

詳細

Published: 1995 Received: 1994/04/28 Available on J-STAGE: 2006/03/30 Accepted: 1994/08/05 Advance online publication: - Revised: -

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A 5-year-old girl and a 2-year-old boy presented with recurrent cerebral primitive neuroectodermal tumor (PNET) and were treated with intravenous administration of human fibroblast interferon (HuIFN-β) which was continued as outpatient maintenance therapy. Both patients showed a partial response and were still alive 14 months and 2 years after diagnosis. Our results suggest that HuIFN-β is an effective therapy for PNET, and can be used as long-term maintenance therapy without serious side effects.

責任著者(Corresponding author)

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