Chlortetracyclineの新Complexに就て

抄録

The calcium and magnesium salts of chlortetracycline were found to be readily soluble in methanol containing either calcium chloride or magnesium chloride. This fact was applied to the isolation of chlortetracycline from cultured broths.
The CaCl₂ complex of chlortetracycline-Ca salt was obtained in a crystalline form, its empirical formula subsequently determined as (C₂₂H₂₁N₂O₈Cl•Ca) 1/2 CaCl₂. This product was very readily soluble in methanol. Similarly, the MgCl₂ complex of chlortetracycline-Mg salt, (C₂₂H₂₁N₂O₈ClMg) 1/2 MgCl₂ was also obtained.