日大医学雑誌
Online ISSN : 1884-0779
Print ISSN : 0029-0424
ISSN-L : 0029-0424
特  集
アルコールを中心として, 栄養障害(ビタミン B1 欠乏症等アルコール関連)
鈴木 貴浩
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ジャーナル フリー

2018 年 77 巻 5 号 p. 309-312

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Nutritional deficiencies are not uncommon. Therefore, we must understand whether nutritional deficiencies can cause cognitive disorder. Wernicke-Korsakoff encephalopathy (WKE), which occurs as a result of thiamine deficiency, pellagra due to nicotinic acid deficiency, malignant anemia, which occurs as a result of vitamin B12 deficiency, and diabetic coma due to hypoglycemia, can all lead to cognitive disorder. We must treat these disorders at the appropriate time, in order to prevent the cognitive disorder from becoming chronic. In this article, we consider WKE. WKE is a metabolic disease that is treatable, when diagnosed in the early stage. In the general setting, it is difficult to diagnose WKE appropriately. Therefore, we must determine whether this nutrition deficiency can contribute to the development of this treatable cognitive disorder.

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