Pancreatic cancer ranks 4th among men and 3rd among women in terms of cancer-related deaths according tothe Cancer Information Service of the National Cancer Center website. The morbidity and mortality are similar,the mortality rate when affected is very high, and the 5-year survival rate for all pancreatic cancer cohorts is 5% to10%, which is the poorest prognosis among several malignant diseases. However, there is much room for improving treatment outcomes.Surgical resection is the only treatment that can be expected to cure pancreatic cancer, but the recurrence rateafter curative resection is very high. It is often the case that it is already unresectable at the time of diagnosis.Regarding surgical resection, despite various surgical improvements, the 5-year survival rate of surgery alone remains at approximately 10% to 20%, and chemotherapy is used not only in unresectable cases but also in resectedcases. The importance of multidisciplinary treatment is increasing.The paper outlines the significance of surgical resection for pancreatic cancer, the evolution of chemotherapy,and future prospects.
