Abstract
Intramitochondrial inclusions in pancreatic acinar cells of the re-fed Japanese newt, Triturus pyrrogaster, following starvation were examined with the aide of an electron microscope. Clusters of mitochondria and the close apposition between mitochondria and rough endoplasmic reticulum were observed in the first few hours after re-feeding. Unusual mitochondria, which were observed in the acinar cells of the starved animals, decreased in number and size after refeeding and finally disappeared. We suggest that intramitochondrial inclusions are temporarily induced as a result of depressed mitochondrial function due to prolonged starvation and also that type III inclusions (crystal or crystalloid) originate from the mitochondrial membrane and matrix.
