Abstract
NC-strain mice in which anaphylactic shock is easily induced were employed. When the mice were sensitized using egg albumin from the whites of eggs as an antigen with allergic conditions, the total number of mast cells which existed in the diencephalon and choroid plexuses was found to increase. The increase was observed especially in the dorsal thalamus, and not in other areas of the diencephalon. The cells in the dorsal thalamus after the initial sensitization were more numerous, and the intensity of fluorescence of histamine was stronger than that of control aminals. Moreover, the intensity range was wider. After the second sensitization dose had been given, the cells were most numerous and the fluorescence of histamine contained in the mast cells displayed a wider range of intensity, indicating an increase in amount.
