新生児髄液中化学物質についての2、3の知見

抄録

Findings of several chemical substances in the CSF of 86 cases of newborn babies (0-14 days of age) were discussed.1. Maxim um values of CSF total protein were about 89 mg% in full term babies and about 200mg% in premature babies. But minimum values of individual cases of intracranial hemorrhage or purulent meningitis were at lowere part of normal range. So we can see some overlap between normal and abnormal range of protein.2. Normal range of CSF gluco se were not so different from the range in normal children. Low glucose values were seen in the cases of hypoglycemia and purulent meningitis, and more remarkable in latter. CSF-blo od ratio of glucose and values of CSF lactate were different between above two diseases. The moving of glucose in CSF may be influenced by intrinsic factors (glycolysis by bac teria or cells) more than extrinsic factors (permeability of blood-CSF-bprrier).3. Normal values of CSF Na, Cl and K were with in normal range of children. Relation of CSF and serum minerals were different between each of Na, Cl and K.