耳鼻咽喉科領域における「グリファナン」の使用経験

抄録

Glifanan, which was known to have anti-inflammatory and analgesic actions, were used for pain due to either inflammation (16 cases) or operation (18 cases). Seventy to ninety percent of the patients treated showed analgesic response. With larger initial dose (600 to 800mgm.), it was found that the more satisfactory analgesic effects could be expected and less dose was required for the maintenance.
In majority of the cases the analgesic effects took place 30 minutes after the administration for the inflammatory pain, while it took more than 50 minutes for the postoperative pain. Side actions, observed on 40% of the cases, were anorexia and nausea. The administration is better interrupted with these side effects. In case Glifanan is used as an anti-inflammatory agent, the dose can be economized with simultaneous use of antibiotics.