Y-5274のアレルギー性鼻炎および血管運動性鼻炎における臨床効果について

Double blind methodによる

抄録

Although antihistaminics are usually effective to improve symptoms caused by allergic rhinitis, they have some drawbacks such as limited duration of the effect or causing drowsiness in some patients.
A new antihistamine Y-5274 was tried in 100 cases of allergic and vasomotor rhinitis and its effect was studied by double blind method.
The dose used was 6 tablets a day for adults and 3 tablets a day for children.
In comparison to a placebo, the active drug showed significant effect for improvement of sneezing, nasal obstruction and nasal discharge.