抄録
Adriamycin is one of the chemotherapeutic agents for treatment of neoplastic diseases. However, the use of this agent is often hindered by its adverse side effects.
Adriamycin ointment was first reported by Fukuda et al. in 1981, and their report described remarkable results when this ointment was used for treatment of local recurrence in breastcancers.
Our newly developed adriamycin ointment was used on a patient with recurrent ethmoidal cancer appearing on the forehead. The patient showed a remarkable improvement with severe necrosis of the tumor when application of this ointment was combined with radiation therapy and hyperthermia. No severe adverse side effects were found except for a slight alopecia.
We conclude that adriamycin ointment is useful as a local chemotherapeutic agent for head and neck cancer patients when used in combination with various other treatments.
