抄録
The incidence of severe sinusitis in Japan has decreased with improvement in the living conditions and development of drugs in recent years.
On the other hand, cases of postoperative maxillary sinus cyst are on the increase.
We attempted to prevent the contraction and closure of the nasoantral window using an artificial collagen film which has attracted attention in recent years. As usual, the maxillary sinus was opened to make an nasoantral window, into which an artificial film was inserted.
This artificial collagen film comes off spontaneously in 2 to 3 weeks.
In cases treated with the artificial collagen film, epithelization around the nasoantral window was accelerated and cure was attained promptly; 11 out of 12 cases showed satisfactory clinical Ichiro, Motokawa course;
In cases not treated with the artificial collagen film, there was hyperplasia of pathologic granulation due to infections, etc.; eight out of 13 cases showed satisfactory clinical course but five had contraction or closure of the nasoantral window.
We embedded an artificial collagen film into the fascia of the thigh muscle in mature rabbits and studied the relationship between the film and the surrounding tissue.
Macroscopically, it looked like a white plate up to the 4th month, became cicatricial thereafter and was absorbed at the 6th month.
Histologically, infiltration of giant cells against foreign body and lymphocytes was hardly observed; the artificial collagen film became swollen and split to be absorbed after the 4th month. Reactions or side-effects of the artificial collagen film was not observed during that period.
The artificial collagen film inhibits hyperplasia of granulation, accelerates epithelization and leads to a cure rapidly without foreign body reaction. This prevents the contraction and closure of the nasoantral window shortly after operation, facilitates outflow of the exudate in the maxillary sinus and results in a higher rate of cure of sinusitis.
The nasoantral window retained by this procedure could possibly prevent postoperative maxillary sinus cysts arising from formation of the obstructed cavity.
