耳鼻咽喉科展望
Online ISSN : 1883-6429
Print ISSN : 0386-9687
ISSN-L : 0386-9687
頭頸部癌に対するフトラフール坐剤の使用経験
放射線, ブレオマイシン併用療法
兵 行和田中 治和久田 幸之助岡坂 利章柏木 令子北奥 恵之藤田 信哉
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1984 年 27 巻 3 号 p. 251-258

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In 29 cases of head and neck carcinoma, radical treatment was performed using three methods consisting Futrafur Suppository (FT-5) +radiotherapy (group 1), FT-S +radiotherapy + BLM, local or intravenous injection, (group 2) and FT-S+ radiotherapy +BLM intra-arterial infusion (group 3) to determine clinical efficancy of each treatment modality. Among the cases, 27 were evaluable.
Primary effect was observed in 26 cases (96.3%) that received radical treatment. One case of group 3 showed no response and died. Local recurrence was observed in six cases (22.2%) in 3-14 months after the initial radical treatment. They were one cases of group 1. two of group 2 and three of group 3. Six cases who were two cases of group 2 and four of group 3 died of the diesease and one case died of a disease unrelated to carcinoma.
Side effect due to the treatment developed in 11 cases (37.9%) out of 29 cases but severe side effect was not encountered.
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