耳鼻咽喉科展望
Online ISSN : 1883-6429
Print ISSN : 0386-9687
ISSN-L : 0386-9687
喉頭癌, 下咽頭癌における癌胎児性抗原 (CEA) の臨床的評価
宮原 裕鶴田 至宏馬谷 克則吉野 邦俊佐藤 武男
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1986 年 29 巻 4 号 p. 405-410

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The level of carcinoembryonic antigen (CEA) was determined in 69 patients with cancer of the larynx and 20 patients with cancer of the hypopharynx. Malignancies were histologically 88 squamous cell carcinomas and one carcinoma in pleomorphic adenoma. The CEA level higher than 5.0ng/ml was considered to be positive. Eleven of 69 (16%) patients with cancer of the larynx and 4 of 20 (20%) patients with cancer of the hypopharynx were positive. The low positive sensitivity of CEA indicated a lesser diagnostic value in cancer of the larynx and hypopharynx. In cancer of the larynx, there was no significant correlation to the clinical stage in the determinations of CEA. The CEA titer elevated with the recurrrence or distant metastasis of the malignancies. It seems that the CEA determination is valuable for monitoring the presence of possible metastasis.
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