抄録
Two kinds of guinea pig animal model of experimental perilymphatic fistula (EPF) are applied in this study. One is “suctioned animal” and the other is “douched animal”. The vestibular findings of EPF animals are as follow, 1) During the acute stage (5 hours postoperatively), spontaneous nystagmus (89.5%) directs to the normal site, which lasts within 24 hours then disappears. 2) During the convalescent stage (1 week postoperatively), directon fixed positional nystagmus (24.6%) instead of spontaneous nystagmus directs to the lesion site. 3) Absent response in ice water caloric test is found in 73.9% of EPF animals.
