A 70-year-old woman visited our hospital with a chief complaint of loss of appetite.
Esophagogastroduodenoscopy revealed edematous and erythematous mucosa in the antrum, the pyloric ring was stenotic and difficult to pass.
Advanced gastric cancer was suspected, however, two boring biopsies reveald no evidence of malignancy.
Endoscopic ultrasound-fine needle aspiration showed proliferative infiltration of atypical cells in the mucosal layer.
Immunohistochemical staining was indicated poorly differentiated adenocarcinoma of epithelial origin, leading to the diagnosis of advanced gastric cancer.
We report a case of advanced gastric cancer in which endoscopic ultrasound-fine needle aspiration was useful in confirming the diagnosis.
