Non-contrast computed tomography (CT) performed on a 61-year-old woman presenting with intermittent abdominal pain revealed an ileal intussusception. Colonoscopy performed at the referring clinic revealed no significant findings, and the patient was referred to our hospital. Contrast-enhanced CT revealed a small intestinal intussusception with a fatty nodule at its leading point. Transanal single-balloon enteroscopy revealed a tumor with surface redness and erosion in the terminal ileum. The tumor was prolapsing into the intestinal lumen. After reducing the intussusception, a detachable snare was placed around the long stalk of the tumor. Owing to insufficient ischemia, repeat enteroscopy was performed the following day, during which polypectomy was successfully completed. Histopathological examination confirmed the identity of a 17-mm lipoma. Although most cases of intussusception caused by lipomas are treated via invasive surgery, this case was successfully managed endoscopically.
