抄録
A 80-year-old male patient referred to our hospital because of constipation and fresh bloody stool. On admission, superficial lymph nodes were palpable in the inguinal resions, and spleno megaly was detected by CT scan examination. Endoscopic examination revealed multiple polypoid lesions in the whole colon, esophagus and duodenum, and tuberous lesions with central depression in the stomach, cecum and rectum. Histopathological examinations of biopsy specimens showed diffuse proliferation of abnormal lymphocytes. Immunohistochemical staining demonstrated that these consisted of L-26, CD-79α positive, and of UCHL1, DFT1, CD3 negative. Consequently this case was diagnosed as B-cell malignant lymphoma, diffusemedium sized cell type. We think that it should be appropriate to deal lymphomatous tumors forming multiple polypoid lesions with distant lymph node involvement as an advanced type of MLP, even if they can not be confirmed as gastrointestinal origin. Further discussion should be raised on diagnostic criteria of MLP.
