抄録
During health assessment of an 81-year-old male, endoscopy detected a depressed lesion with ulceration in the lower esophagus. Histological analysis of biopsies diagnosed squamous cell carcinoma, but the findings were atypical and─due to the histological appearance of glandular structures─there was suspicion of basaloid squamous carcinoma (BSC). Lower esophagectomy was performed, and histology of resected tissue demonstrated BSC mixed of trabecular components and glandular structures, with squamous cell carcinoma in-situ at the border of the ulcerative lesion. The final histological diagnosis was：carcinoma with mixed basaloid squamous and glandular differentiation, pT1b(SM3), INFc, ly0, v1, N0, M0. BSC of the esophagus is a rare but distinct variant of esophageal carcinoma, and the incidence of BSC has been reported as 1.3% of total esophageal malignant tumors. Histologically, esophageal BSC displays a variety of features, but few cases show glandular structures. We describe an unusual case report of esophageal BSC with glandular differentiation.
