抄録
A 47-year-old male was referred to our clinic because GERD was suspected based on the frequency scale for the symptoms of GERD (FFSG) . Upper gastrointestinal endoscopy showed rough whitish mucosa, loss of vascularity, and the presence of linear furrows and mucosal rings throughout the esophagus. Histological examination of biopsy specimens revealed marked infiltration of more than 50 eosinophils per high power field (HPF) in the esophageal mucosa and slight infiltration of about 2 eosinophils/HPF in the gastric mucosa. The patient was diagnosed with eosinophilic esophagitis (EE) based on diagnostic guidelines for the disease. He was prescribed an oral proton pump inhibitor (PPI) and although the patient’s symptoms improved, endoscopic and histologic findings did not change remarkably. Therefore, an oral administration of fluticasone inhalation was initiated, which resulted in improvement of endoscopic and histologic findings. Reports of EE are rare in Japan. Therefore, this case is considered to have some clinical significance in establishing this disease concept.
