A 71-year-old woman who had been diagnosed as chronic nonspecific multiple ulcers of the small intestine (CNSU) at the age of 25, and ileocecal resection was performed for the ileal stenosis in total three times. The patient had abdominal pain, vomiting from March X year. Colonoscopy was performed to investigate these symptoms. The shallow ulcer with stenosis was observed in the 3 to 4 cm oral side from the ileocecal anastomosis. The stenosis was successfully treated by endoscopic balloon dilatation, and this case was avoided surgical resection. This case was positive for SLCO2A1 gene mutation which was considered as a causative gene mutation of CNSU.
