A male in his fifties who had been diagnosed as adenocarcinoma of esophagogastric junction by screening endoscopy. Esophagoscopy revealed a 15mm- slightly elevated lesion (Paris type 0-IIa) locating on the left wall of the esophagogastric junction. ESD was performed as a purpose of total biopsy. The final pathological diagnosis was Barrett's esophageal cancer, with deep submucosal invasion. It is consistent with that the tumor arose from Barrett's epithelium, since non-neoplastic glandular epithelium with intestinal metaplasia was found adjacent to the tumor. ESD enables secure resection and precise pathological diagnosis, thus contributes to decide indication of surgery for patients with Barrett's adenocarcinoma.
