Two cases of sebaceous glands in the esophagus were diagnosed by panendoscopy and biopsy. Endoscopy disclosed a flat elevated round granular, yellowish lesion in the middle esophagus.
As sebaceous glands is an ectodermal origin, it is very rare that we observe it in the esophagus, an endodermal origin. But we found two new cases with sebaceous glands in the esophagus during a half year. Twenty-one cases including our 2 cases during endoscopy have been reported. We consider that frequency of sebaceous glands in the esophagus will be increasing if we perform endoscopy strictly.