胃癌と大腸癌を合併した多発性骨髄腫の1例

抄録

A 73-year-old man who complained of bloody stool was pointed out to have two polyps of sigmoid colon and admitted to our hospital for further examination and treatment.
On admission, mild anemia (Hb 10.5ｇ/dl) and hypergam maglobulinemia (36.1%) were observed. Serum immunoglobulin G (IgG) value was high (3,872 mg/dl) . In immunological electrophoresis, monoclonal gammopathy of IgG_κ type was observed and Bence-Jones protein in urine was positive. The bone marrow was occupied by atypical plasma cells. After all he was diagnosed multiple myeloma of IgG_κ type.
He had two plypes at the sigmoid colon, one polype was polypectomized under colonoscopy and proved to be a cancer in adenoma ; the other polyp was a cancer invading in proper muscle layer and surgically resected. The upper GI series and endoscopic examination revealed a gastric cancer of Borrman 3 type, about 5 cm in size, in the lesser curvature of gastric cardia.
We reported a rare case of multiple myeloma complicated with both gastric and sigmoid colon cancers.