The effect of Helicobacter pylori (Hp) eradication on duodenal ulcer healing was studied in 24 patients with duodenal ulcer (16 males and 8 females, mean age : 41 years old) . Eradication was done with lansoprazole 30mg/day 6 weeks and amoxicillin 1,500mg/day 2 weeks. Hp infection was detected by serum Hp IgG antibody, rapid urease test, histological examination and 13C urea breath test.
The follwing results was obtained.
1) Endoscopic findings at clearance : In total, S1 stage was 50% and S2 stage was 50%. S1 stage was 100% in Hp positive cases and S1 stage was 33% and S2 stage was 67% in Hp negative cases.
2) Endoscopic findings at eradication : S1 stage was 100% in Hp positive cases and S2 stage was 100% in Hp negative cases.
From these results showed above, it is suggested that Hp eradication effect healing rate to S2 stage, also in relapsed cases. Because eradication rates was only 50%, however we must consider about the combination of medicine, duration of therapy and so on.
