A 52-year-old male with 4 month-long periumbilical discomfort, dull pain, and weight loss of 10kg in four months was admitted for examinations. On admission he had periumbilical tenderness and marked eosinophilia (59% of 16,900/mm3 peripheral leukocyte count) .
Endoscopic examination showed mucosal roughness and indistinct vascular pattern of esophagus, enlargement of Kerckring's folds and redness at 2nd portion of duodenum, and biopsy specimens taken from these lesions revealed prominent infiltration of eosinophils. Stomach and colon mucosa were almost endoscopically normal, and their specimens showed mild infiltration of eosinophils. Abdominal CT and US indicated swelling of gall bladder.
He was observed without specific treatment, such as steroids or anti-allergic agents, however, his symptoms improved gradually and laboratory findings normalized. After 6 months, he was symptomless.
