微小膵癌の1例

抄録

A 72-year-old male, who visited our hospital for diabetes mellitus, was pointed out abnormality on pancreas and admitted to our hospital for further examination. Abdominal US, CT, MRI and EUS showed a cyst 7mm in diameter in the pancreatic body and dilatation of the main pancreatic duct (MPD) in the pancreatic body and tail. ERP showed severe localized stenosis of the MPD in the pancreatic body, with proximal duct dilatation. The result of cytologic examination of the pancreatic juice was class IIIa.
Under the diagnosis of pancreatic cancer, distal pancreatectomy was performed. Histopathological study showed inflammatory cells and marked fibrosis but no tumor tissues around the stenotic part of the MPD. And it showed carcinoma in situ approximately 5mm in size mainly presented in the branch of the pancreatic duct and partially in the MPD in the distal portion. p53 staining showed diffusely positive pattern in the carcinoma.