A 26-year-old female was admitted to our hospital because of lasting retrosternal burning pain and back pain after taking a doxycycline tablet. It was taken with little water just going to bed 5 days ago.
Esophagoscopy revealed circular ulcers with clot in the lower esophagus in 3cm length (34cm from incisors) . She was diagnosed as doxycycline-induced esophageal ulcers by endoscopic findings and course, and treated with H2-receptor antagonist under nothing by mouth. On the 15th day after the onset, endoscopy showed marked improvement. The follow-up esophagoscopy performed 3 month later showed disapperance of the ulcers with scars.
There have been several reports of solitary ulcer induced by doxycycline tablet. However very few cases of circular ulcers caused by the tablet have been reported.
