Helicobacter pylori感染からみた組織学的胃炎像―The Sydney Systemに基づく―

抄録

The degree of activity, atrophy, intestinal metaplasia and Helicobacter pylori (Hp) were observed based on the Sydney System in gastric biopsy specimen and their relationship were also estimated.
(1) Observation of histological activity and Hp infection : In biopsy specimen at the greater curvature of lower antrum, Hp infection grade 0 was the most predominat in activity grade 0. Activity score related to Hp was same in the greater curvature of upper body and the lesser curvature of lower body.
(2) Relationship between atrophy and Hp : The degree of atrophic change and Hp were observed in biopsy specimen at the lesser curvature of lower body. Hp grade 3 was the most freguent in atrophy grade 1. We couldn't find a difference on Hp grade in atrophy grade 2 and 3.
(3) Relationship between atrophic change and intestinal metaplasia : Severe intestinal metaplasia cases were low in atrophic grade 1. With the increase of atrophic grade, intestinal metaplasia grade increased gradually.